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Predicting Growth Conditions from Internal Metabolic Fluxes in an In-Silico Model of E. coli
A widely studied problem in systems biology is to predict bacterial phenotype from growth conditions, using mechanistic models such as flux balance analysis (FBA). However, the inverse prediction of growth conditions from phenotype is rarely considered. Here we develop a computational framework to c...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264753/ https://www.ncbi.nlm.nih.gov/pubmed/25502413 http://dx.doi.org/10.1371/journal.pone.0114608 |