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Combination of Cyclopamine and Tamoxifen Promotes Survival and Migration of MCF-7 Breast Cancer Cells – Interaction of Hedgehog-Gli and Estrogen Receptor Signaling Pathways
Hedgehog-Gli (Hh-Gli) signaling pathway is one of the new molecular targets found upregulated in breast tumors. Estrogen receptor alpha (ERα) signaling has a key role in the development of hormone-dependent breast cancer. We aimed to investigate the effects of inhibiting both pathways simultaneously...
Autores principales: | Sabol, Maja, Trnski, Diana, Uzarevic, Zvonimir, Ozretic, Petar, Musani, Vesna, Rafaj, Maja, Cindric, Mario, Levanat, Sonja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264763/ https://www.ncbi.nlm.nih.gov/pubmed/25503972 http://dx.doi.org/10.1371/journal.pone.0114510 |
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