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Egr-1 Activation by Cancer-Derived Extracellular Vesicles Promotes Endothelial Cell Migration via ERK1/2 and JNK Signaling Pathways

Various mammalian cells, including cancer cells, shed extracellular vesicles (EVs), also known as exosomes and microvesicles, into surrounding tissues. These EVs play roles in tumor growth and metastasis by promoting angiogenesis. However, the detailed mechanism of how cancer-derived EVs elicit endo...

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Detalles Bibliográficos
Autores principales: Yoon, Yae Jin, Kim, Dae-Kyum, Yoon, Chang Min, Park, Jaesung, Kim, Yoon-Keun, Roh, Tae-Young, Gho, Yong Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264882/
https://www.ncbi.nlm.nih.gov/pubmed/25502753
http://dx.doi.org/10.1371/journal.pone.0115170

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