Mass spectrometry-based proteomics in Chest Medicine, Gerontology, and Nephrology: subgroups omics for personalized medicine

Mass spectrometry (MS) is currently the most promising tool for studying proteomics to investigate largescale proteins in a specific proteome. Emerging MS-based proteomics is widely applied to decipher complex proteome for discovering potential biomarkers. Given its growing usage in clinical medicin...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Shih-Yi, Hsu, Wu-Huei, Lin, Cheng-Chieh, Chen, Chao-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: China Medical University 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264973/
https://www.ncbi.nlm.nih.gov/pubmed/25520938
http://dx.doi.org/10.7603/s40681-014-0025-y
_version_ 1782348809152495616
author Lin, Shih-Yi
Hsu, Wu-Huei
Lin, Cheng-Chieh
Chen, Chao-Jung
author_facet Lin, Shih-Yi
Hsu, Wu-Huei
Lin, Cheng-Chieh
Chen, Chao-Jung
author_sort Lin, Shih-Yi
collection PubMed
description Mass spectrometry (MS) is currently the most promising tool for studying proteomics to investigate largescale proteins in a specific proteome. Emerging MS-based proteomics is widely applied to decipher complex proteome for discovering potential biomarkers. Given its growing usage in clinical medicine for biomarker discovery to predict, diagnose and confer prognosis, MS-based proteomics can benefit study of personalized medicine. In this review we introduce some fundamental MS theory and MS-based quantitative proteomic approaches as well as several representative clinical MS-based proteomics issues in Chest Medicine, Gerontology, and Nephrology.
format Online
Article
Text
id pubmed-4264973
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher China Medical University
record_format MEDLINE/PubMed
spelling pubmed-42649732014-12-15 Mass spectrometry-based proteomics in Chest Medicine, Gerontology, and Nephrology: subgroups omics for personalized medicine Lin, Shih-Yi Hsu, Wu-Huei Lin, Cheng-Chieh Chen, Chao-Jung Biomedicine (Taipei) Review Article Mass spectrometry (MS) is currently the most promising tool for studying proteomics to investigate largescale proteins in a specific proteome. Emerging MS-based proteomics is widely applied to decipher complex proteome for discovering potential biomarkers. Given its growing usage in clinical medicine for biomarker discovery to predict, diagnose and confer prognosis, MS-based proteomics can benefit study of personalized medicine. In this review we introduce some fundamental MS theory and MS-based quantitative proteomic approaches as well as several representative clinical MS-based proteomics issues in Chest Medicine, Gerontology, and Nephrology. China Medical University 2014-11-13 /pmc/articles/PMC4264973/ /pubmed/25520938 http://dx.doi.org/10.7603/s40681-014-0025-y Text en © China Medical University 2014 https://creativecommons.org/licenses/by/4.0/ Open Access This article is distributed under terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided original author(s) and source are credited.
spellingShingle Review Article
Lin, Shih-Yi
Hsu, Wu-Huei
Lin, Cheng-Chieh
Chen, Chao-Jung
Mass spectrometry-based proteomics in Chest Medicine, Gerontology, and Nephrology: subgroups omics for personalized medicine
title Mass spectrometry-based proteomics in Chest Medicine, Gerontology, and Nephrology: subgroups omics for personalized medicine
title_full Mass spectrometry-based proteomics in Chest Medicine, Gerontology, and Nephrology: subgroups omics for personalized medicine
title_fullStr Mass spectrometry-based proteomics in Chest Medicine, Gerontology, and Nephrology: subgroups omics for personalized medicine
title_full_unstemmed Mass spectrometry-based proteomics in Chest Medicine, Gerontology, and Nephrology: subgroups omics for personalized medicine
title_short Mass spectrometry-based proteomics in Chest Medicine, Gerontology, and Nephrology: subgroups omics for personalized medicine
title_sort mass spectrometry-based proteomics in chest medicine, gerontology, and nephrology: subgroups omics for personalized medicine
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264973/
https://www.ncbi.nlm.nih.gov/pubmed/25520938
http://dx.doi.org/10.7603/s40681-014-0025-y
work_keys_str_mv AT linshihyi massspectrometrybasedproteomicsinchestmedicinegerontologyandnephrologysubgroupsomicsforpersonalizedmedicine
AT hsuwuhuei massspectrometrybasedproteomicsinchestmedicinegerontologyandnephrologysubgroupsomicsforpersonalizedmedicine
AT linchengchieh massspectrometrybasedproteomicsinchestmedicinegerontologyandnephrologysubgroupsomicsforpersonalizedmedicine
AT chenchaojung massspectrometrybasedproteomicsinchestmedicinegerontologyandnephrologysubgroupsomicsforpersonalizedmedicine

Ejemplares similares