Personalized medicine in Type 2 Diabetes

Type 2 diabetes (T2D) is a global public health concern, its prevalence in Asia, especially Taiwan, rising every year. The risk of developing T2D and diabetes complications is not only controlled by environmental but also by genetic factors. Genetic association studies have shown polymorphisms at sp...

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Detalles Bibliográficos
Autores principales: Liao, Wen-Ling, Tsai, Fuu-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: China Medical University 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264975/
https://www.ncbi.nlm.nih.gov/pubmed/25520921
http://dx.doi.org/10.7603/s40681-014-0008-z
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author Liao, Wen-Ling
Tsai, Fuu-Jen
author_facet Liao, Wen-Ling
Tsai, Fuu-Jen
author_sort Liao, Wen-Ling
collection PubMed
description Type 2 diabetes (T2D) is a global public health concern, its prevalence in Asia, especially Taiwan, rising every year. The risk of developing T2D and diabetes complications is not only controlled by environmental but also by genetic factors. Genetic association studies have shown polymorphisms at specific loci may help identify individuals at greatest risk and response to oral antidiabetic drugs. This review probes effect of genetic profiling on T2D and its complications, using our study population as examples. Also, pharmacogenetics and pharmacogenomics of oral anitdiabetic drug will be explored.
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spelling pubmed-42649752014-12-15 Personalized medicine in Type 2 Diabetes Liao, Wen-Ling Tsai, Fuu-Jen Biomedicine (Taipei) Article Type 2 diabetes (T2D) is a global public health concern, its prevalence in Asia, especially Taiwan, rising every year. The risk of developing T2D and diabetes complications is not only controlled by environmental but also by genetic factors. Genetic association studies have shown polymorphisms at specific loci may help identify individuals at greatest risk and response to oral antidiabetic drugs. This review probes effect of genetic profiling on T2D and its complications, using our study population as examples. Also, pharmacogenetics and pharmacogenomics of oral anitdiabetic drug will be explored. China Medical University 2014-08-06 /pmc/articles/PMC4264975/ /pubmed/25520921 http://dx.doi.org/10.7603/s40681-014-0008-z Text en © China Medical University 2014 https://creativecommons.org/licenses/by/4.0/ Open Access. This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Article
Liao, Wen-Ling
Tsai, Fuu-Jen
Personalized medicine in Type 2 Diabetes
title Personalized medicine in Type 2 Diabetes
title_full Personalized medicine in Type 2 Diabetes
title_fullStr Personalized medicine in Type 2 Diabetes
title_full_unstemmed Personalized medicine in Type 2 Diabetes
title_short Personalized medicine in Type 2 Diabetes
title_sort personalized medicine in type 2 diabetes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264975/
https://www.ncbi.nlm.nih.gov/pubmed/25520921
http://dx.doi.org/10.7603/s40681-014-0008-z
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