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EZH2: novel therapeutic target for human cancer
Enhancer of Zeste homlog 2 (EZH2) is a catalytic subunit of epigenetic regulator Polycomb repressive complex 2 (PRC2), which trimethylates Lys 27 of histone H3, leading to silencing of the target genes that are involved in a variety of biological processes including tumor progression and stem cell m...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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China Medical University
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264983/ https://www.ncbi.nlm.nih.gov/pubmed/25520914 http://dx.doi.org/10.7603/s40681-014-0001-6 |