First isolation and genomic characterization of enterovirus A71 and coxsackievirus A16 from hand foot and mouth disease patients in the Lao PDR

Enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) are major aetiological agents of hand, foot and mouth disease in Asia. We established the first genomic characterization of strains isolated in 2011 from Lao patients. Isolates were related to EV-A71 genotype C4 and CV-A16 genotype B1a that ci...

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Autores principales: Nguyen, V H, Sibounheuang, B, Phommasone, K, Vongsouvath, M, Newton, P N, Piorkowski, G, Baronti, C, de Lamballerie, X, Dubot-Pérès, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
New Genomes of Microorganisms and Viruses in Humans
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265048/
https://www.ncbi.nlm.nih.gov/pubmed/25566395
http://dx.doi.org/10.1002/nmi2.63
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author Nguyen, V H
Sibounheuang, B
Phommasone, K
Vongsouvath, M
Newton, P N
Piorkowski, G
Baronti, C
de Lamballerie, X
Dubot-Pérès, A
author_facet Nguyen, V H
Sibounheuang, B
Phommasone, K
Vongsouvath, M
Newton, P N
Piorkowski, G
Baronti, C
de Lamballerie, X
Dubot-Pérès, A
author_sort Nguyen, V H
collection PubMed
description Enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) are major aetiological agents of hand, foot and mouth disease in Asia. We established the first genomic characterization of strains isolated in 2011 from Lao patients. Isolates were related to EV-A71 genotype C4 and CV-A16 genotype B1a that circulated in neighbouring countries during the same period. This confirms the regional character of hand, foot and mouth disease epidemiology and makes plausible the occurrence of severe disease in the Lao population.
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spelling pubmed-42650482015-01-06 First isolation and genomic characterization of enterovirus A71 and coxsackievirus A16 from hand foot and mouth disease patients in the Lao PDR Nguyen, V H Sibounheuang, B Phommasone, K Vongsouvath, M Newton, P N Piorkowski, G Baronti, C de Lamballerie, X Dubot-Pérès, A New Microbes New Infect New Genomes of Microorganisms and Viruses in Humans Enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) are major aetiological agents of hand, foot and mouth disease in Asia. We established the first genomic characterization of strains isolated in 2011 from Lao patients. Isolates were related to EV-A71 genotype C4 and CV-A16 genotype B1a that circulated in neighbouring countries during the same period. This confirms the regional character of hand, foot and mouth disease epidemiology and makes plausible the occurrence of severe disease in the Lao population. BlackWell Publishing Ltd 2014-11 2014-09-18 /pmc/articles/PMC4265048/ /pubmed/25566395 http://dx.doi.org/10.1002/nmi2.63 Text en © 2014 The Authors. New Microbes and New Infections published by John Wiley & Sons Ltd on behalf of the European Society of Clinical Microbiology and Infectious Disease. http://creativecommons.org/licenses/by/3.0/ This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle New Genomes of Microorganisms and Viruses in Humans
Nguyen, V H
Sibounheuang, B
Phommasone, K
Vongsouvath, M
Newton, P N
Piorkowski, G
Baronti, C
de Lamballerie, X
Dubot-Pérès, A
First isolation and genomic characterization of enterovirus A71 and coxsackievirus A16 from hand foot and mouth disease patients in the Lao PDR
title First isolation and genomic characterization of enterovirus A71 and coxsackievirus A16 from hand foot and mouth disease patients in the Lao PDR
title_full First isolation and genomic characterization of enterovirus A71 and coxsackievirus A16 from hand foot and mouth disease patients in the Lao PDR
title_fullStr First isolation and genomic characterization of enterovirus A71 and coxsackievirus A16 from hand foot and mouth disease patients in the Lao PDR
title_full_unstemmed First isolation and genomic characterization of enterovirus A71 and coxsackievirus A16 from hand foot and mouth disease patients in the Lao PDR
title_short First isolation and genomic characterization of enterovirus A71 and coxsackievirus A16 from hand foot and mouth disease patients in the Lao PDR
title_sort first isolation and genomic characterization of enterovirus a71 and coxsackievirus a16 from hand foot and mouth disease patients in the lao pdr
topic New Genomes of Microorganisms and Viruses in Humans
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265048/
https://www.ncbi.nlm.nih.gov/pubmed/25566395
http://dx.doi.org/10.1002/nmi2.63
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