Effect of L-type calcium channel blocker (amlodipine) on myocardial iron deposition in patients with thalassaemia with moderate-to-severe myocardial iron deposition: protocol for a randomised, controlled trial

INTRODUCTION: Sideroblastic cardiomyopathy secondary to repeated blood transfusions is a feared complication in thalassaemia. Control of myocardial iron is thus becoming the cornerstone of thalassaemia management. Recent evidence suggests a role for L-type Ca(2+) channels in mediating iron uptake by...

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Detalles Bibliográficos
Autores principales: Shakoor, Amarah, Zahoor, Maaman, Sadaf, Alina, Alvi, Najveen, Fadoo, Zehra, Rizvi, Arjumand, Quadri, Farheen, Tipoo, Fateh Ali, Khurshid, Mohammad, Sajjad, Zaffar, Colan, Steven, Hasan, Babar S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Paediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265146/
https://www.ncbi.nlm.nih.gov/pubmed/25492271
http://dx.doi.org/10.1136/bmjopen-2014-005360

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