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Surface modifications of influenza proteins upon virus inactivation by β-propiolactone*

Inactivation of intact influenza viruses using formaldehyde or β-propiolactone (BPL) is essential for vaccine production and safety. The extent of chemical modifications of such reagents on viral proteins needs to be extensively investigated to better control the reactions and quality of vaccines. W...

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Detalles Bibliográficos
Autores principales: She, Yi-Min, Cheng, Keding, Farnsworth, Aaron, Li, Xuguang, Cyr, Terry D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265195/
https://www.ncbi.nlm.nih.gov/pubmed/24123778
http://dx.doi.org/10.1002/pmic.201300096

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