Cargando…

Oligomerization status influences subcellular deposition and glycosylation of recombinant butyrylcholinesterase in Nicotiana benthamiana

Plants have a proven track record for the expression of biopharmaceutically interesting proteins. Importantly, plants and mammals share a highly conserved secretory pathway that allows similar folding, assembly and posttranslational modifications of proteins. Human butyrylcholinesterase (BChE) is a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schneider, Jeannine D, Marillonnet, Sylvestre, Castilho, Alexandra, Gruber, Clemens, Werner, Stefan, Mach, Lukas, Klimyuk, Victor, Mor, Tsafrir S, Steinkellner, Herta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265266/ https://www.ncbi.nlm.nih.gov/pubmed/24618259 http://dx.doi.org/10.1111/pbi.12184

Ejemplares similares

Identification of two subtilisin‐like serine proteases engaged in the degradation of recombinant proteins in Nicotiana benthamiana
por: Puchol Tarazona, Alejandro A., et al.
Publicado: (2020)

Reduced paucimannosidic N‐glycan formation by suppression of a specific β‐hexosaminidase from Nicotiana benthamiana
por: Shin, Yun‐Ji, et al.
Publicado: (2016)

An oligosaccharyltransferase from Leishmania major increases the N‐glycan occupancy on recombinant glycoproteins produced in Nicotiana benthamiana
por: Castilho, Alexandra, et al.
Publicado: (2018)

Transient Expression of Tetrameric Recombinant Human Butyrylcholinesterase in Nicotiana benthamiana
por: Alkanaimsh, Salem, et al.
Publicado: (2016)

Expression Profiling and Glycan Engineering of IgG Subclass 1–4 in Nicotiana benthamiana
por: Kallolimath, Somanath, et al.
Publicado: (2020)

Vacuolar targeting of recombinant antibodies in Nicotiana benthamiana
por: Ocampo, Carolina Gabriela, et al.
Publicado: (2016)

Transient proteolysis reduction of Nicotiana benthamiana-produced CAP256 broadly neutralizing antibodies using CRISPR/Cas9
por: Singh, Advaita Acarya, et al.
Publicado: (2022)

Biological and biochemical characterization of HIV-1 Gag/dgp41 virus-like particles expressed in Nicotiana benthamiana
por: Kessans, Sarah A, et al.
Publicado: (2013)

Engineering of human-type O-glycosylation in Nicotiana benthamiana plants
por: Strasser, Richard
Publicado: (2013)

Site-Specific Glycosylation of Recombinant Viral Glycoproteins Produced in Nicotiana benthamiana
por: Margolin, Emmanuel, et al.
Publicado: (2021)

In vitro and in vivo efficacy of anti‐chikungunya virus monoclonal antibodies produced in wild‐type and glycoengineered Nicotiana benthamiana plants
por: Hurtado, Jonathan, et al.
Publicado: (2019)

Transient Expression of Glycosylated SARS-CoV-2 Antigens in Nicotiana benthamiana
por: Ruocco, Valentina, et al.
Publicado: (2022)

The Subcellular Localization and Functional Analysis of Fibrillarin2, a Nucleolar Protein in Nicotiana benthamiana
por: Zheng, Luping, et al.
Publicado: (2016)

Comparative analysis of plant transient expression vectors for targeted N-glycosylation
por: Eidenberger, Lukas, et al.
Publicado: (2022)

Generation of enzymatically competent SARS‐CoV‐2 decoy receptor ACE2‐Fc in glycoengineered Nicotiana benthamiana
por: Castilho, Alexandra, et al.
Publicado: (2021)

Reversal of Succinylcholine Induced Apnea with an Organophosphate Scavenging Recombinant Butyrylcholinesterase
por: Geyer, Brian C., et al.
Publicado: (2013)

Nicotiana benthamiana Class 1 Reversibly Glycosylated Polypeptides Suppress Tobacco Mosaic Virus Infection
por: Kamarova, Kamila A., et al.
Publicado: (2023)

Genome and transcriptome characterization of the glycoengineered Nicotiana benthamiana line ΔXT/FT
por: Schiavinato, Matteo, et al.
Publicado: (2019)

Investigation of the N-Glycosylation of the SARS-CoV-2 S Protein Contained in VLPs Produced in Nicotiana benthamiana
por: Balieu, Juliette, et al.
Publicado: (2022)

Engineering of Sialylated Mucin-type O-Glycosylation in Plants
por: Castilho, Alexandra, et al.
Publicado: (2012)

Agroinfiltration and PVX Agroinfection in Potato and Nicotiana benthamiana
por: Du, Juan, et al.
Publicado: (2014)

Parental origin of the allotetraploid tobacco Nicotiana benthamiana
por: Schiavinato, Matteo, et al.
Publicado: (2020)

Arginine/Lysine Residues in the Cytoplasmic Tail Promote ER Export of Plant Glycosylation Enzymes
por: Schoberer, Jennifer, et al.
Publicado: (2009)

Characterization of plants expressing the human β1,4-galactosyltrasferase gene
por: Schneider, Jeannine, et al.
Publicado: (2015)

Reconstitution of the Costunolide Biosynthetic Pathway in Yeast and Nicotiana benthamiana
por: Liu, Qing, et al.
Publicado: (2011)

Nicotiana benthamiana as a Production Platform for Artemisinin Precursors
por: van Herpen, Teun W. J. M., et al.
Publicado: (2010)

Reproducibility and flexibility of monoclonal antibody production with Nicotiana benthamiana
por: Swope, Kelsi, et al.
Publicado: (2022)

Transient Expression of Flavivirus Structural Proteins in Nicotiana benthamiana
por: Asghar, Naveed, et al.
Publicado: (2022)

Tunable control of insect pheromone biosynthesis in Nicotiana benthamiana
por: Kallam, Kalyani, et al.
Publicado: (2023)

Production and N-glycan engineering of Varlilumab in Nicotiana benthamiana
por: Nguyen, Kim Dua, et al.
Publicado: (2023)

Functional divergence of an immune receptor complex in Nicotiana benthamiana
por: Laflamme, Bradley
Publicado: (2023)

N-Glycosylation of cholera toxin B subunit in Nicotiana benthamiana: impacts on host stress response, production yield and vaccine potential
por: Hamorsky, Krystal Teasley, et al.
Publicado: (2015)

N-Glycosylation engineering of plants for the biosynthesis of glycoproteins with bisected and branched complex N-glycans
por: Castilho, Alexandra, et al.
Publicado: (2011)

Virus Infection Suppresses Nicotiana benthamiana Adaptive Phenotypic Plasticity
por: Bedhomme, Stéphanie, et al.
Publicado: (2011)

Virus-induced Gene Silencing (VIGS) in Nicotiana benthamiana and Tomato
por: Velásquez, André C., et al.
Publicado: (2009)

High-level diterpene production by transient expression in Nicotiana benthamiana
por: Brückner, Kathleen, et al.
Publicado: (2013)

Optimization of Engineered Production of the Glucoraphanin Precursor Dihomomethionine in Nicotiana benthamiana
por: Crocoll, Christoph, et al.
Publicado: (2016)

The production of human glucocerebrosidase in glyco‐engineered Nicotiana benthamiana plants
por: Limkul, Juthamard, et al.
Publicado: (2016)

The Production of Human β-Glucocerebrosidase in Nicotiana benthamiana Root Culture
por: Naphatsamon, Uthailak, et al.
Publicado: (2018)

Improving agroinfiltration-based transient gene expression in Nicotiana benthamiana
por: Norkunas, Karlah, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_sv1jmhpe7g62o9a4d7979rbn2g