PNPLA3 I148M (rs738409) genetic variant and age at onset of at-risk alcohol consumption are independent risk factors for alcoholic cirrhosis

BACKGROUND & AIMS: Environmental and genetic factors contribute to alcoholic cirrhosis onset. In particular, age at exposure to liver stressors has been shown to be important in progression to fibrosis in hepatitis C individuals. However, no definite data on the role of age at onset of at-risk a...

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Detalles Bibliográficos
Autores principales: Burza, Maria Antonella, Molinaro, Antonio, Attilia, Maria Luisa, Rotondo, Claudia, Attilia, Fabio, Ceccanti, Mauro, Ferri, Flaminia, Maldarelli, Federica, Maffongelli, Angela, De Santis, Adriano, Attili, Adolfo Francesco, Romeo, Stefano, Ginanni Corradini, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Cirrhosis and Liver Failure
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265268/
https://www.ncbi.nlm.nih.gov/pubmed/24102786
http://dx.doi.org/10.1111/liv.12310

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