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Targets for future clinical trials in Huntington's disease: What's in the pipeline?
The known genetic cause of Huntington's disease (HD) has fueled considerable progress in understanding its pathobiology and the development of therapeutic approaches aimed at correcting specific changes linked to the causative mutation. Among the most promising is reducing expression of mutant...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265300/ https://www.ncbi.nlm.nih.gov/pubmed/25155142 http://dx.doi.org/10.1002/mds.26007 |