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Upregulation of death receptor 5 and activation of caspase 8/3 play a critical role in ergosterol peroxide induced apoptosis in DU 145 prostate cancer cells

BACKGROUND: Though ergosterol peroxide (EP) derived from Neungyi mushrooms (Sarcodon aspratus) was known to have cytotoxic, apoptotic, anti-inflammatory and antimycobacterial effects, the underlying molecular mechanism of EP still remains unclear. Thus, in the present study, the apoptotic mechanism...

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Detalles Bibliográficos
Autores principales:	Han, Jonghyun, Sohn, Eun Jung, Kim, Bonglee, Kim, Sunhee, Won, Gunho, Yoon, Sangwook, Lee, Jihyun, Kim, Moon Joon, Lee, Hojin, Chung, Kyujin, Kim, Sung-hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265345/ https://www.ncbi.nlm.nih.gov/pubmed/25506265 http://dx.doi.org/10.1186/s12935-014-0117-5

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