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Hydrogen sulfide-releasing cyclooxygenase inhibitor ATB-346 enhances motor function and reduces cortical lesion volume following traumatic brain injury in mice

BACKGROUND: Traumatic brain injury (TBI) induces secondary injury mechanisms, including dynamic interplay between ischemic, inflammatory and cytotoxic processes. We recently reported that administration of ATB-346 (2-(6-methoxynapthalen- 2-yl)-propionic acid 4-thiocarbamoyl-phenyl ester), a hydrogen...

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Detalles Bibliográficos
Autores principales:	Campolo, Michela, Esposito, Emanuela, Ahmad, Akbar, Di Paola, Rosanna, Paterniti, Irene, Cordaro, Marika, Bruschetta, Giuseppe, Wallace, John L, Cuzzocrea, Salvatore
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265354/ https://www.ncbi.nlm.nih.gov/pubmed/25472548 http://dx.doi.org/10.1186/s12974-014-0196-1

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