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Inhibition of AMPK expression in skeletal muscle by systemic inflammation in COPD rats

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a disease characterized by airflow limitation and inflammation. Meanwhile, COPD also is associated with metabolic disorders, such as skeletal muscle weakness. Strikingly, activation of AMP-activated protein kinase (AMPK) exerts critical rol...

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Detalles Bibliográficos
Autores principales: Qi, Yong, Shang, Jun-yi, Ma, Li-jun, Sun, Bei-bei, Hu, Xin-gang, Liu, Bao, Zhang, Guo-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265440/
https://www.ncbi.nlm.nih.gov/pubmed/25481457
http://dx.doi.org/10.1186/s12931-014-0156-4