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Growth and metastasis of B16-F10 melanoma cells is not critically dependent on host CD73 expression in mice
BACKGROUND: Recent studies have suggested that adenosine generated by ecto-5′-nucleotidase (CD73) in the tumor microenvironment plays a major role in promoting tumor growth by suppressing the immune response and stimulating angiogenesis via A2A and A2B receptors. However, adenosine has also been rep...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265456/ https://www.ncbi.nlm.nih.gov/pubmed/25465225 http://dx.doi.org/10.1186/1471-2407-14-898 |