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Next generation sequencing reads comparison with an alignment-free distance

BACKGROUND: Next Generation Sequencing (NGS) machines extract from a biological sample a large number of short DNA fragments (reads). These reads are then used for several applications, e.g., sequence reconstruction, DNA assembly, gene expression profiling, mutation analysis. METHODS: We propose a m...

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Detalles Bibliográficos
Autores principales: Weitschek, Emanuel, Santoni, Daniele, Fiscon, Giulia, De Cola, Maria Cristina, Bertolazzi, Paola, Felici, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265526/
https://www.ncbi.nlm.nih.gov/pubmed/25465386
http://dx.doi.org/10.1186/1756-0500-7-869