Cargando…

Synaptotagmin-7 links fusion-activated Ca(2+) entry and fusion pore dilation

Ca(2+)-dependent regulation of fusion pore dilation and closure is a key mechanism determining the output of cellular secretion. We have recently described ‘fusion-activated’ Ca(2+) entry (FACE) following exocytosis of lamellar bodies in alveolar type II cells. FACE regulates fusion pore expansion a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Neuland, Kathrin, Sharma, Neeti, Frick, Manfred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265738/ https://www.ncbi.nlm.nih.gov/pubmed/25344253 http://dx.doi.org/10.1242/jcs.153742

Ejemplares similares

Vesicular control of fusion pore expansion
por: Neuland, Kathrin, et al.
Publicado: (2015)

The neuronal calcium sensor Synaptotagmin-1 and SNARE proteins cooperate to dilate fusion pores
por: Wu, Zhenyong, et al.
Publicado: (2021)

Regulation of Exocytosis and Fusion Pores by Synaptotagmin-Effector Interactions
por: Zhang, Zhen, et al.
Publicado: (2010)

Synaptotagmin-7 outperforms synaptotagmin-1 to promote the formation of large, stable fusion pores via robust membrane penetration
por: Courtney, Kevin C., et al.
Publicado: (2023)

Molecular origins of synaptotagmin 1 activities on vesicle docking and fusion pore opening
por: Lai, Ying, et al.
Publicado: (2015)

Synaptotagmin VII Restricts Fusion Pore Expansion during Lysosomal Exocytosis
por: Jaiswal, Jyoti K, et al.
Publicado: (2004)

Distinct fusion properties of synaptotagmin-1 and synaptotagmin-7 bearing dense core granules
por: Rao, Tejeshwar C., et al.
Publicado: (2014)

Structural basis for the clamping and Ca(2+) activation of SNARE-mediated fusion by synaptotagmin
por: Grushin, Kirill, et al.
Publicado: (2019)

Ca(2+) and cAMP open differentially dilating synaptic fusion pores
por: Bulgari, Dinara, et al.
Publicado: (2023)

Dilation of fusion pores by crowding of SNARE proteins
por: Wu, Zhenyong, et al.
Publicado: (2017)

Conserved arginine residues in synaptotagmin 1 regulate fusion pore expansion through membrane contact
por: Nyenhuis, Sarah B., et al.
Publicado: (2021)

Molecular mechanism of the synaptotagmin–SNARE interaction in Ca(2+)-triggered vesicle fusion
por: Vrljic, Marija, et al.
Publicado: (2010)

Fusion-Activated Ca(2+) Entry: An “Active Zone” of Elevated Ca(2+) during the Postfusion Stage of Lamellar Body Exocytosis in Rat Type II Pneumocytes
por: Miklavc, Pika, et al.
Publicado: (2010)

Cytotoxic Granule Trafficking and Fusion in Synaptotagmin7-Deficient Cytotoxic T Lymphocytes
por: Sleiman, Marwa, et al.
Publicado: (2020)

α-Synuclein Promotes Dilation of the Exocytotic Fusion Pore
por: Logan, Todd, et al.
Publicado: (2017)

The synaptotagmin C2B domain calcium-binding loops modulate the rate of fusion pore expansion
por: Bendahmane, Mounir, et al.
Publicado: (2018)

Dilation of the influenza hemagglutinin fusion pore revealed by the kinetics of individual cell-cell fusion events
Publicado: (1996)

Synaptotagmin oligomers are necessary and can be sufficient to form a Ca(2+)‐sensitive fusion clamp
por: Ramakrishnan, Sathish, et al.
Publicado: (2019)

Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca(2+)
por: Chicka, Michael C, et al.
Publicado: (2008)

Reconstituted synaptotagmin I mediates vesicle docking, priming, and fusion
por: Wang, Zhao, et al.
Publicado: (2011)

Fusion pores with low conductance are cation selective
por: Delacruz, Joannalyn B., et al.
Publicado: (2021)

A synaptotagmin suppressor screen indicates SNARE binding controls the timing and Ca(2+) cooperativity of vesicle fusion
por: Guan, Zhuo, et al.
Publicado: (2017)

Cdc42 controls the dilation of the exocytotic fusion pore by regulating membrane tension
por: Bretou, Marine, et al.
Publicado: (2014)

Fusion pore expansion is a slow, discontinuous, and Ca(2+)-dependent process regulating secretion from alveolar type II cells
por: Haller, Thomas, et al.
Publicado: (2001)

Calcium-independent stimulation of membrane fusion and SNAREpin formation by synaptotagmin I
por: Mahal, Lara K., et al.
Publicado: (2002)

Synaptotagmin rings as high-sensitivity regulators of synaptic vesicle docking and fusion
por: Zhu, Jie, et al.
Publicado: (2022)

Human LAMP1 accelerates Lassa virus fusion and potently promotes fusion pore dilation upon forcing viral fusion with non-endosomal membrane
por: Zhang, You, et al.
Publicado: (2022)

The exocytotic fusion pore
Publicado: (1992)

Temperature Dependence of Fusion Kinetics and Fusion Pores in Ca(2+)-triggered Exocytosis from PC12 Cells
por: Zhang, Zhen, et al.
Publicado: (2008)

Single-molecule FRET-derived model of the synaptotagmin 1–SNARE fusion complex
por: Choi, Ucheor B., et al.
Publicado: (2010)

Calcium/synaptotagmin-evoked compound fusion increases quantal size and synaptic strength
por: He, Liming, et al.
Publicado: (2009)

Synaptotagmin 1 clamps synaptic vesicle fusion in mammalian neurons independent of complexin
por: Courtney, Nicholas A., et al.
Publicado: (2019)

Synaptotagmin C2B Domain Regulates Ca(2+)-triggered Fusion in Vitro: CRITICAL RESIDUES REVEALED BY SCANNING ALANINE MUTAGENESIS
por: Gaffaney, Jon D., et al.
Publicado: (2008)

Synaptotagmin-1 drives synchronous Ca(2+) triggered fusion by C(2)B domain-mediated synaptic vesicle-membrane attachment
por: Chang, Shuwen, et al.
Publicado: (2017)

Synaptotagmin 7 functions as a Ca(2+)-sensor for synaptic vesicle replenishment
por: Liu, Huisheng, et al.
Publicado: (2014)

Synaptotagmin-7 Enhances Facilitation of Ca(v)2.1 Calcium Channels
por: Djillani, Alaeddine, et al.
Publicado: (2022)

Synaptotagmin Function Illuminated
por: Lindau, Manfred
Publicado: (2003)

Alphavirus Entry and Membrane Fusion
por: Kielian, Margaret, et al.
Publicado: (2010)

Entry and Fusion of Emerging Paramyxoviruses
por: Dutch, Rebecca Ellis
Publicado: (2010)

Exocytotic fusion pore under stress
por: Chowdhury, Helena Haque, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_06dv080jfgdvrbf44so2cc4v59