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ATRX is required for maintenance of the neuroprogenitor cell pool in the embryonic mouse brain
Mutations in the alpha-thalassemia mental retardation X-linked (ATRX) gene cause a spectrum of abnormalities including intellectual disability, developmental delay, seizures, and microcephaly. The ATRX protein is highly enriched at heterochromatic repetitive sequences adjacent to the centromere, and...
Autores principales: | Ritchie, Kieran, Watson, L. Ashley, Davidson, Benjamin, Jiang, Yan, Bérubé, Nathalie G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265753/ https://www.ncbi.nlm.nih.gov/pubmed/25395668 http://dx.doi.org/10.1242/bio.20148730 |
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