High levels of SIRT1 expression enhance tumorigenesis and associate with a poor prognosis of colorectal carcinoma patients

SIRT1, a NAD(+) dependent class III deacetylase, takes part in many important biological processes. Previous studies show that SIRT1 is overexpressed in some cancers and plays an essential role in tumorigenesis. However, the association between SIRT1 and colorectal cancer (CRC) is still unclear. We...

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Detalles Bibliográficos
Autores principales: Chen, Xiaojing, Sun, Kai, Jiao, Shufan, Cai, Ning, Zhao, Xue, Zou, Hanbing, Xie, Yuexia, Wang, Zhengshi, Zhong, Ming, Wei, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265776/
https://www.ncbi.nlm.nih.gov/pubmed/25500546
http://dx.doi.org/10.1038/srep07481

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