Loss of ion transporters and increased unfolded protein response in Fuchs’ dystrophy

PURPOSE: Fuchs’ endothelial corneal dystrophy (FECD), which affects approximately 5% of the population over 40 in the U.S.A., is a major cause of corneal transplantation. FECD is associated with mutations of a variety of unrelated genes: SLC4A11, COL8A2, TCF8, and LOXHD1. The current pathological de...

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Detalles Bibliográficos
Autores principales: Jalimarada, Supriya S., Ogando, Diego G., Bonanno, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265779/
https://www.ncbi.nlm.nih.gov/pubmed/25548511

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