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Transcriptional Repression by the BRG1-SWI/SNF Complex Affects the Pluripotency of Human Embryonic Stem Cells

The SWI/SNF complex plays an important role in mouse embryonic stem cells (mESCs), but it remains to be determined whether this complex is required for the pluripotency of human ESCs (hESCs). Using RNAi, we demonstrated that depletion of BRG1, the catalytic subunit of the SWI/SNF complex, led to imp...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiaoli, Li, Bing, Li, Wenguo, Ma, Lijuan, Zheng, Dongyan, Li, Leping, Yang, Weijing, Chu, Min, Chen, Wei, Mailman, Richard B., Zhu, Jun, Fan, Guoping, Archer, Trevor K., Wang, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266000/ https://www.ncbi.nlm.nih.gov/pubmed/25241744 http://dx.doi.org/10.1016/j.stemcr.2014.07.004

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