Derivation and Expansion of PAX7-Positive Muscle Progenitors from Human and Mouse Embryonic Stem Cells

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Cell therapies treating pathological muscle atrophy or damage requires an adequate quantity of muscle progenitor cells (MPCs) not currently attainable from adult donors. Here, we generate cultures of approximately 90% skeletal myogenic cells by treating human embryonic stem cells (ESCs) with the GSK...

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Detalles Bibliográficos
Autores principales: Shelton, Michael, Metz, Jeff, Liu, Jun, Carpenedo, Richard L., Demers, Simon-Pierre, Stanford, William L., Skerjanc, Ilona S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266001/
https://www.ncbi.nlm.nih.gov/pubmed/25241748
http://dx.doi.org/10.1016/j.stemcr.2014.07.001
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