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Secreted frizzled-related protein 1 regulates adipose tissue expansion and is dysregulated in severe obesity

AIM: The Wnt/β-catenin signalling network offers potential targets to diagnose and uncouple obesity from its metabolic complications. Here we investigate the role of the Wnt antagonist, secreted Frizzled related protein 1 (SFRP1) in promoting adipogenesis in vitro and adipose tissue expansion in viv...

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Detalles Bibliográficos
Autores principales:	Lagathu, Claire, Christodoulides, Constantinos, Tan, Chong Yew, Virtue, Sam, Laudes, Matthias, Campbell, Mark, Ishikawa, Ko, Ortega, Francisco, Tinahones, Francisco J., Fernández-Real, Jose-Manuel, Orešič, Matej, Sethi, Jaswinder K., Vidal-Puig, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266104/ https://www.ncbi.nlm.nih.gov/pubmed/20514047 http://dx.doi.org/10.1038/ijo.2010.107

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