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Functions of lncRNA HOTAIR in lung cancer

Long non-coding RNAs (lncRNAs) govern fundamental biochemical and cellular processes. lncRNA HOX transcript antisense RNA (HOTAIR) represses gene expression through recruitment of chromatin modifiers. The expression of HOTAIR is elevated in lung cancer and correlates with metastasis and poor prognos...

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Detalles Bibliográficos
Autores principales:	Loewen, Gregory, Jayawickramarajah, Janarthanan, Zhuo, Ying, Shan, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266198/ https://www.ncbi.nlm.nih.gov/pubmed/25491133 http://dx.doi.org/10.1186/s13045-014-0090-4

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