Cargando…

New Type of BACE1 siRNA Delivery to Cells

BACKGROUND: Small interfering RNA (siRNA) gene therapy is a new molecular approach in the search for an efficient therapy for Alzheimer disease (AD), based on the principle of RNA interference. Reducing BACE activity can have great therapeutic potential for the treatment of AD. In this study, recept...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jabłkowski, Maciej, Szemraj, Maciej, Oszajca, Katarzyna, Janiszewska, Grażyna, Bartkowiak, Jacek, Szemraj, Janusz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2014
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266366/ https://www.ncbi.nlm.nih.gov/pubmed/25491230 http://dx.doi.org/10.12659/MSM.891219

Ejemplares similares

MicroRNA Expression Analysis in Serum of Patients with Congenital Hemochromatosis and Age-Related Macular Degeneration (AMD)
por: Szemraj, Maciej, et al.
Publicado: (2017)

The study of t-PA, u-PA and PAI-1 genes polymorphisms in patients with abdominal aortic aneurysm
por: Oszajca, Katarzyna, et al.
Publicado: (2014)

Association analysis of genetic polymorphisms of factor V, factor VII and fibrinogen β chain genes with human abdominal aortic aneurysm
por: OSZAJCA, KATARZYNA, et al.
Publicado: (2012)

Adenovirus-Mediated siRNA Targeting CXCR2 Attenuates Titanium Particle-Induced Osteolysis by Suppressing Osteoclast Formation
por: Wang, Chen, et al.
Publicado: (2016)

Assessment of the correlation between oxidative stress and expression of MMP-2, TIMP-1 and COX-2 in human aortic smooth muscle cells
por: Oszajca, Katarzyna, et al.
Publicado: (2021)

siRNAs: in vitro activity against SARS virus
Publicado: (2013)

Serum MicroRNAs as Potential Biomarkers of AMD
por: Szemraj, Maciej, et al.
Publicado: (2015)

The Interplay between Insulin Resistance, Inflammation, Oxidative Stress, Base Excision Repair and Metabolic Syndrome in Nonalcoholic Fatty Liver Disease
por: Ziolkowska, Sylwia, et al.
Publicado: (2021)

MicroRNA profile and iron-related gene expression in hepatitis C-related hepatocellular carcinoma: a preliminary study
por: Krupa, Renata, et al.
Publicado: (2019)

Exosomes as nanocarriers for siRNA delivery: paradigms and challenges
por: Shahabipour, Fahimeh, et al.
Publicado: (2016)

A Long Noncoding RNA (lncRNA)-Associated Competing Endogenous RNA (ceRNA) Network Identifies Eight lncRNA Biomarkers in Patients with Osteoarthritis of the Knee
por: Chen, Yuxi, et al.
Publicado: (2019)

High RNA-Binding Motif Protein 3 (RBM3) Expression is Independently Associated with Prolonged Overall Survival in Intestinal-Type Gastric Cancer
por: Ye, Fangpeng, et al.
Publicado: (2017)

Nano-Hydroxyapatite-Derived Drug and Gene Co-Delivery System for Anti-Angiogenesis Therapy of Breast Cancer
por: Zhao, Lina, et al.
Publicado: (2017)

Identification of Potentially Functional CircRNA-miRNA-mRNA Regulatory Network in Gastric Carcinoma using Bioinformatics Analysis
por: Yang, Guodong, et al.
Publicado: (2019)

Genome-Wide Profiling of miRNA and mRNA Expression in Alzheimer’s Disease
por: Chang, Wan-Sheng, et al.
Publicado: (2017)

The Long Non-Coding RNA (lncRNA) AGAP2-AS1 is Upregulated in Ovarian Carcinoma and Negatively Regulates lncRNA MEG3
por: Chen, Jingjing, et al.
Publicado: (2019)

Expression of Micro-RNA-492 (MiR-492) in Human Cervical Cancer Cell Lines is Upregulated by Transfection with Wild-Type P53, Irradiation, and 5-Fluorouracil Treatment In Vitro
por: Liu, Mei, et al.
Publicado: (2018)

Long Non-Coding RNA (lncRNA) Small Nucleolar RNA Host Gene 15 (SNHG15) Alleviates Osteoarthritis Progression by Regulation of Extracellular Matrix Homeostasis
por: Chen, Yunping, et al.
Publicado: (2020)

Functional Long Noncoding RNAs (lncRNAs) in Clear Cell Kidney Carcinoma Revealed by Reconstruction and Comprehensive Analysis of the lncRNA–miRNA–mRNA Regulatory Network
por: Zhu, Hehuan, et al.
Publicado: (2018)

MicroRNA-495 Inhibits New Bone Regeneration via Targeting High Mobility Group AT-Hook 2 (HMGA2)
por: Tian, Zhao, et al.
Publicado: (2017)

Long-Chain Non-Coding RNA (lncRNA) MT1JP Suppresses Biological Activities of Lung Cancer by Regulating miRNA-423-3p/Bim Axis
por: Ma, Jiyong, et al.
Publicado: (2019)

Long Noncoding RNA (lncRNA) Small Nucleolar RNA Host Gene 5 (SNHG5) Regulates Proliferation, Differentiation, and Apoptosis of K562 Cells in Chronic Myeliod Leukemia
por: Gao, Bing, et al.
Publicado: (2019)

Effect of Low-Frequency Pulsed Ultrasound on Drug Delivery, Antibacterial Efficacy, and Bone Cement Degradation in Vancomycin-Loaded Calcium Phosphate Cement
por: Shi, Mingmin, et al.
Publicado: (2018)

Detection and Analysis of the Hedgehog Signaling Pathway-Related Long Non-Coding RNA (lncRNA) Expression Profiles in Keloid
por: Huang, Heping, et al.
Publicado: (2018)

Identification of Potential Diagnostic and Prognostic Pseudogenes in Hepatocellular Carcinoma Based on Pseudogene-miRNA-mRNA Competitive Network
por: Yan, Lijun, et al.
Publicado: (2020)

Antiviral Activity of Hatay Propolis Against Replication of Herpes Simplex Virus Type 1 and Type 2
por: Yildirim, Ayse, et al.
Publicado: (2016)

Expression of the Long Intergenic Non-Coding RNA (lincRNA) of the NED25 Gene Modulates the microRNA-125b, STAT3, Nitric Oxide, and Procalcitonin Signaling Pathways in Patients with Sepsis
por: Le, Yuanjie, et al.
Publicado: (2018)

Identification of RNA Expression Profiles in Thyroid Cancer to Construct a Competing Endogenous RNA (ceRNA) Network of mRNAs, Long Noncoding RNAs (lncRNAs), and microRNAs (miRNAs)
por: Xu, Yuanxin, et al.
Publicado: (2019)

Knockdown of Long Noncoding RNA (lncRNA) AK094457 Relieved Angiotensin II Induced Vascular Endothelial Cell Injury
por: Xu, JiaYi, et al.
Publicado: (2020)

Long Noncoding RNA (lncRNA) n379519 Promotes Cardiac Fibrosis in Post-Infarct Myocardium by Targeting miR-30
por: Wang, Xiaxia, et al.
Publicado: (2018)

Long Non-Coding RNA (LncRNA) HOXA11-AS Promotes Breast Cancer Invasion and Metastasis by Regulating Epithelial-Mesenchymal Transition
por: Li, Wenlei, et al.
Publicado: (2017)

Long Non-Coding RNA (LncRNA) UFC1/miR-34a Contributes to Proliferation and Migration in Breast Cancer
por: Xie, Ruilian, et al.
Publicado: (2019)

RNA Binding Protein RNPC1 Suppresses the Stemness of Human Endometrial Cancer Cells via Stabilizing MST1/2 mRNA
por: Wu, XingMei, et al.
Publicado: (2020)

Silencing of Long Non-Coding RNA (LncRNA) Non-Coding RNA Activated by DNA Damage (NORAD) Inhibits Proliferation, Invasion, Migration, and Promotes Apoptosis of Glioma Cells via Downregulating the Expression of AKR1B1
por: Luo, Lun, et al.
Publicado: (2020)

Prognostic Value of Dynactin mRNA Expression in Cutaneous Melanoma
por: Wang, Qiaoqi, et al.
Publicado: (2018)

Long Non-Coding RNA (lncRNA) NEAT1 Aggravates Cerebral Ischemia-Reperfusion Injury by Suppressing the Inhibitory Effect of miR-214 on PTEN
por: Shen, Shouyin, et al.
Publicado: (2020)

Long Noncoding RNA (lncRNA) FOXD2-AS1 Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma by Regulating MiR-185/AKT Axis
por: Chen, Zheng, et al.
Publicado: (2019)

Long Non-Coding RNA (lncRNA) CRNDE Regulated Lipopolysaccharides (LPS)-Induced MRC-5 Inflammation Injury Through Targeting MiR-141
por: Tang, Xingping, et al.
Publicado: (2020)

Long Noncoding RNA Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1) Promotes Renal Cell Carcinoma Progression via Sponging miRNA-429
por: Jiang, Lin-Tao, et al.
Publicado: (2018)

Long Non-Coding RNA (lncRNA) X-Inactive Specific Transcript (XIST) Plays a Critical Role in Predicting Clinical Prognosis and Progression of Colorectal Cancer
por: Zhang, Xiu-Tian, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_1e95jjfd2cfpit5i21tr2vp7jj