Possible protective role of the 489C>T P2X7R polymorphism in Alzheimer's disease

Inflammation is a key factor in the onset and progression of Alzheimer's disease (AD). The P2X7 receptor (P2X7R) is increasingly recognized as key pro-inflammatory receptor. A recent study has shown that activation of microglia by amyloid β (Aβ) and associated release of IL-1β, requires P2X7R e...

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Detalles Bibliográficos
Autores principales: Sanz, Juana M., Falzoni, Simonetta, Rizzo, Roberta, Cipollone, Francesco, Zuliani, Giovanni, Di Virgilio, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266448/
https://www.ncbi.nlm.nih.gov/pubmed/25456845
http://dx.doi.org/10.1016/j.exger.2014.10.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266448/
https://www.ncbi.nlm.nih.gov/pubmed/25456845
http://dx.doi.org/10.1016/j.exger.2014.10.009

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