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Role of mitogen-activated protein kinase phosphatase-1 in corticosteroid insensitivity of chronic oxidant lung injury
Oxidative stress plays an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD) and in the induction of corticosteroid (CS) insensitivity. Chronic ozone exposure leads to a model of COPD with lung inflammation and emphysema. Mitogen-activated protein kinase phosphatase-1...
Autores principales: | Pinart, Mariona, Hussain, Farhana, Shirali, Sima, Li, Feng, Zhu, Jie, Clark, Andrew R., Ammit, Alaina J., Chung, Kian Fan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266539/ https://www.ncbi.nlm.nih.gov/pubmed/25310910 http://dx.doi.org/10.1016/j.ejphar.2014.10.003 |
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