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Protoporphyrins Enhance Oligomerization and Enzymatic Activity of HtrA1 Serine Protease

High temperature requirement protein A1 (HtrA1), a secreted serine protease of the HtrA family, is associated with a multitude of human diseases. However, the exact functions of HtrA1 in these diseases remain poorly understood. We seek to unravel the mechanisms of HtrA1 by elucidating its interactio...

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Detalles Bibliográficos
Autores principales: Jo, Hakryul, Patterson, Victoria, Stoessel, Sean, Kuan, Chia-Yi, Hoh, Josephine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266670/
https://www.ncbi.nlm.nih.gov/pubmed/25506911
http://dx.doi.org/10.1371/journal.pone.0115362

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