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Protoporphyrins Enhance Oligomerization and Enzymatic Activity of HtrA1 Serine Protease
High temperature requirement protein A1 (HtrA1), a secreted serine protease of the HtrA family, is associated with a multitude of human diseases. However, the exact functions of HtrA1 in these diseases remain poorly understood. We seek to unravel the mechanisms of HtrA1 by elucidating its interactio...
Autores principales: | Jo, Hakryul, Patterson, Victoria, Stoessel, Sean, Kuan, Chia-Yi, Hoh, Josephine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266670/ https://www.ncbi.nlm.nih.gov/pubmed/25506911 http://dx.doi.org/10.1371/journal.pone.0115362 |
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