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Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discovery
The Trypanosomatidae family, composed of unicellular parasites, causes severe vector-borne diseases that afflict human populations worldwide. Chagas disease, sleeping sickness, as well as different sorts of leishmaniases are amongst the most important infectious diseases produced by Trypanosoma cruz...
Autores principales: | Balaña-Fouce, Rafael, Álvarez-Velilla, Raquel, Fernández-Prada, Christopher, García-Estrada, Carlos, Reguera, Rosa M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266802/ https://www.ncbi.nlm.nih.gov/pubmed/25516844 http://dx.doi.org/10.1016/j.ijpddr.2014.07.006 |
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