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Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana
Classical pharmacology has been the basis for the discovery of new chemical entities with therapeutic effects for decades. In natural product research, compounds are generally tested in vivo only after full in vitro characterization. However drug screening using this methodology is expensive, time-c...
Autores principales: | Simoes-Pires, Claudia, Hostettmann, Kurt, Haouala, Amina, Cuendet, Muriel, Falquet, Jacques, Graz, Bertrand, Christen, Philippe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266807/ https://www.ncbi.nlm.nih.gov/pubmed/25516845 http://dx.doi.org/10.1016/j.ijpddr.2014.07.001 |
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