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Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana

Classical pharmacology has been the basis for the discovery of new chemical entities with therapeutic effects for decades. In natural product research, compounds are generally tested in vivo only after full in vitro characterization. However drug screening using this methodology is expensive, time-c...

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Detalles Bibliográficos
Autores principales: Simoes-Pires, Claudia, Hostettmann, Kurt, Haouala, Amina, Cuendet, Muriel, Falquet, Jacques, Graz, Bertrand, Christen, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266807/
https://www.ncbi.nlm.nih.gov/pubmed/25516845
http://dx.doi.org/10.1016/j.ijpddr.2014.07.001

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