Synovial T cell hyporesponsiveness to myeloid dendritic cells is reversed by preventing PD-1/PD-L1 interactions

INTRODUCTION: The aim of this study was to investigate PD-1/PD-L1 involvement in the hyporesponsiveness of rheumatoid arthritis (RA) synovial fluid (SF) CD4 T cells upon stimulation by thymic stromal lymphopoietin (TSLP)–primed CD1c myeloid dendritic cells (mDCs). METHODS: Expression of PD-1 on naïv...

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Detalles Bibliográficos
Autores principales: Moret, Frederique M, van der Wurff-Jacobs, Kim MG, Bijlsma, Johannes WJ, Lafeber, Floris PJG, van Roon, Joel AG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266919/
https://www.ncbi.nlm.nih.gov/pubmed/25433812
http://dx.doi.org/10.1186/s13075-014-0497-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266919/
https://www.ncbi.nlm.nih.gov/pubmed/25433812
http://dx.doi.org/10.1186/s13075-014-0497-x

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