GPKOW is essential for pre-mRNA splicing in vitro and suppresses splicing defect caused by dominant-negative DHX16 mutation in vivo

Human GPKOW [G-patch (glycine-rich) domain and KOW (Kyrpides, Ouzounis and Woese) domain] protein contains a G-patch domain and two KOW domains, and is a homologue of Arabidopsis MOS2 and Saccharomyces Spp2 protein. GPKOW is found in the human spliceosome, but its role in pre-mRNA splicing remains t...

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Detalles Bibliográficos
Autores principales: Zang, Shengbing, Lin, Ting-Yu, Chen, Xinji, Gencheva, Marieta, Newo, Alain N. S., Yang, Lixin, Rossi, Daniel, Hu, Jianda, Lin, Shwu-Bin, Huang, Aimin, Lin, Ren-Jang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266926/
https://www.ncbi.nlm.nih.gov/pubmed/25296192
http://dx.doi.org/10.1042/BSR20140142

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