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Inflammation and ER Stress Downregulate BDH2 Expression and Dysregulate Intracellular Iron in Macrophages

Macrophages play a very important role in host defense and in iron homeostasis by engulfing senescent red blood cells and recycling iron. Hepcidin is the master iron regulating hormone that limits dietary iron absorption from the gut and limits iron egress from macrophages. Upon infection macrophage...

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Detalles Bibliográficos
Autores principales: Zughaier, Susu M., Stauffer, Brandon B., McCarty, Nael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267003/
https://www.ncbi.nlm.nih.gov/pubmed/25762501
http://dx.doi.org/10.1155/2014/140728

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