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Proteasome inhibition slightly improves cardiac function in mice with hypertrophic cardiomyopathy
A growing line of evidence indicates a dysfunctional ubiquitin-proteasome system (UPS) in cardiac diseases. Anti-hypertrophic effects and improved cardiac function have been reported after treatment with proteasome inhibitors in experimental models of cardiac hypertrophy. Here we tested whether prot...
Autores principales: | Schlossarek, Saskia, Singh, Sonia R., Geertz, Birgit, Schulz, Herbert, Reischmann, Silke, Hübner, Norbert, Carrier, Lucie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267180/ https://www.ncbi.nlm.nih.gov/pubmed/25566086 http://dx.doi.org/10.3389/fphys.2014.00484 |
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