Anti-Inflammatory and Immunomodulatory Mechanism of Tanshinone IIA for Atherosclerosis

Tanshinone IIA (Tan II A) is widely used in the treatment of cardiovascular diseases as an active component of Salvia miltiorrhiza Bunge. It has been demonstrated to have pleiotropic effects for atherosclerosis. From the anti-inflammatory and immunomodulatory mechanism perspective, this paper review...

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Detalles Bibliográficos
Autores principales: Chen, Zhuo, Xu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267215/
https://www.ncbi.nlm.nih.gov/pubmed/25525444
http://dx.doi.org/10.1155/2014/267976
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author Chen, Zhuo
Xu, Hao
author_facet Chen, Zhuo
Xu, Hao
author_sort Chen, Zhuo
collection PubMed
description Tanshinone IIA (Tan II A) is widely used in the treatment of cardiovascular diseases as an active component of Salvia miltiorrhiza Bunge. It has been demonstrated to have pleiotropic effects for atherosclerosis. From the anti-inflammatory and immunomodulatory mechanism perspective, this paper reviewed major progresses of Tan IIA in antiatherosclerosis research, including immune cells, antigens, cytokines, and cell signaling pathways.
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spelling pubmed-42672152014-12-18 Anti-Inflammatory and Immunomodulatory Mechanism of Tanshinone IIA for Atherosclerosis Chen, Zhuo Xu, Hao Evid Based Complement Alternat Med Review Article Tanshinone IIA (Tan II A) is widely used in the treatment of cardiovascular diseases as an active component of Salvia miltiorrhiza Bunge. It has been demonstrated to have pleiotropic effects for atherosclerosis. From the anti-inflammatory and immunomodulatory mechanism perspective, this paper reviewed major progresses of Tan IIA in antiatherosclerosis research, including immune cells, antigens, cytokines, and cell signaling pathways. Hindawi Publishing Corporation 2014 2014-12-02 /pmc/articles/PMC4267215/ /pubmed/25525444 http://dx.doi.org/10.1155/2014/267976 Text en Copyright © 2014 Z. Chen and H. Xu. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Chen, Zhuo
Xu, Hao
Anti-Inflammatory and Immunomodulatory Mechanism of Tanshinone IIA for Atherosclerosis
title Anti-Inflammatory and Immunomodulatory Mechanism of Tanshinone IIA for Atherosclerosis
title_full Anti-Inflammatory and Immunomodulatory Mechanism of Tanshinone IIA for Atherosclerosis
title_fullStr Anti-Inflammatory and Immunomodulatory Mechanism of Tanshinone IIA for Atherosclerosis
title_full_unstemmed Anti-Inflammatory and Immunomodulatory Mechanism of Tanshinone IIA for Atherosclerosis
title_short Anti-Inflammatory and Immunomodulatory Mechanism of Tanshinone IIA for Atherosclerosis
title_sort anti-inflammatory and immunomodulatory mechanism of tanshinone iia for atherosclerosis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267215/
https://www.ncbi.nlm.nih.gov/pubmed/25525444
http://dx.doi.org/10.1155/2014/267976
work_keys_str_mv AT chenzhuo antiinflammatoryandimmunomodulatorymechanismoftanshinoneiiaforatherosclerosis
AT xuhao antiinflammatoryandimmunomodulatorymechanismoftanshinoneiiaforatherosclerosis

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