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Gain-of-function CCR4 mutations in adult T cell leukemia/lymphoma
Adult T cell leukemia/lymphoma (ATLL) is an aggressive malignancy caused by human T cell lymphotropic virus type-I (HTLV-I) without curative treatment at present. To illuminate the pathogenesis of ATLL we performed whole transcriptome sequencing of purified ATLL patient samples and discovered recurr...
Autores principales: | Nakagawa, Masao, Schmitz, Roland, Xiao, Wenming, Goldman, Carolyn K., Xu, Weihong, Yang, Yandan, Yu, Xin, Waldmann, Thomas A., Staudt, Louis M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267233/ https://www.ncbi.nlm.nih.gov/pubmed/25488980 http://dx.doi.org/10.1084/jem.20140987 |
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