The molecular bases of δ/αβ T cell–mediated antigen recognition

αβ and γδ T cells are disparate T cell lineages that can respond to distinct antigens (Ags) via the use of the αβ and γδ T cell Ag receptors (TCRs), respectively. Here we characterize a population of human T cells, which we term δ/αβ T cells, expressing TCRs comprised of a TCR-δ variable gene (Vδ1)...

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Detalles Bibliográficos
Autores principales: Pellicci, Daniel G., Uldrich, Adam P., Le Nours, Jérôme, Ross, Fiona, Chabrol, Eric, Eckle, Sidonia B.G., de Boer, Renate, Lim, Ricky T., McPherson, Kirsty, Besra, Gurdyal, Howell, Amy R., Moretta, Lorenzo, McCluskey, James, Heemskerk, Mirjam H.M., Gras, Stephanie, Rossjohn, Jamie, Godfrey, Dale I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267242/
https://www.ncbi.nlm.nih.gov/pubmed/25452463
http://dx.doi.org/10.1084/jem.20141764

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