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Establishment of comparative performance criteria for IVF centers: correlation of live birth rates in autologous and donor oocyte IVF cycles
BACKGROUND: To assess whether an objective performance criterion for in vitro fertilization (IVF) centers can be established. METHODS: A retrospective analysis of 2011 National ART Surveillance System data for 451 U.S. IVF centers, 137 of which were included in the analysis since they performed >...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267438/ https://www.ncbi.nlm.nih.gov/pubmed/25475407 http://dx.doi.org/10.1186/1477-7827-12-122 |
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author | Kushnir, Vitaly A Khanna, Pallavi Barad, David H Gleicher, Norbert |
author_facet | Kushnir, Vitaly A Khanna, Pallavi Barad, David H Gleicher, Norbert |
author_sort | Kushnir, Vitaly A |
collection | PubMed |
description | BACKGROUND: To assess whether an objective performance criterion for in vitro fertilization (IVF) centers can be established. METHODS: A retrospective analysis of 2011 National ART Surveillance System data for 451 U.S. IVF centers, 137 of which were included in the analysis since they performed >20 fresh embryo transfers per age group and >20 fresh oocyte donor transfers. The analysis of autologous cycles was restricted to women under age 40. The main outcome measure was correlation between center-specific live birth rates (LBR) in autologous and donor oocyte cycles. RESULTS: 55.6% donor and 46.7%, 39.1% and 28.7% (for ages <35, 35–37 and 38–40 years) autologous cycles resulted in live births per fresh embryo transfer. Donor LBR predicted autologous LBR (< 35 years, P < 0.001; 35 – 38 years, P < 0.001; 38 – 40 years, P = 0.015). Clinics with high prevalence of patients with diminished ovarian reserve had lower autologous LBR per age group (P = 0.015). Every 10% increase in donor LBR increased odds of autologous LBR above the age-adjusted national average by 68% (OR 1.68; 95% CI 1.36 – 2.07; P < 0.001). CONCLUSIONS: Since center-specific donor and autologous IVF cycle outcomes correlate, and as donor cycles reflect fewer patient covariates, they represent a first comparable performance measure between centers, allowing for internal as well as external quality control. |
format | Online Article Text |
id | pubmed-4267438 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-42674382014-12-17 Establishment of comparative performance criteria for IVF centers: correlation of live birth rates in autologous and donor oocyte IVF cycles Kushnir, Vitaly A Khanna, Pallavi Barad, David H Gleicher, Norbert Reprod Biol Endocrinol Research BACKGROUND: To assess whether an objective performance criterion for in vitro fertilization (IVF) centers can be established. METHODS: A retrospective analysis of 2011 National ART Surveillance System data for 451 U.S. IVF centers, 137 of which were included in the analysis since they performed >20 fresh embryo transfers per age group and >20 fresh oocyte donor transfers. The analysis of autologous cycles was restricted to women under age 40. The main outcome measure was correlation between center-specific live birth rates (LBR) in autologous and donor oocyte cycles. RESULTS: 55.6% donor and 46.7%, 39.1% and 28.7% (for ages <35, 35–37 and 38–40 years) autologous cycles resulted in live births per fresh embryo transfer. Donor LBR predicted autologous LBR (< 35 years, P < 0.001; 35 – 38 years, P < 0.001; 38 – 40 years, P = 0.015). Clinics with high prevalence of patients with diminished ovarian reserve had lower autologous LBR per age group (P = 0.015). Every 10% increase in donor LBR increased odds of autologous LBR above the age-adjusted national average by 68% (OR 1.68; 95% CI 1.36 – 2.07; P < 0.001). CONCLUSIONS: Since center-specific donor and autologous IVF cycle outcomes correlate, and as donor cycles reflect fewer patient covariates, they represent a first comparable performance measure between centers, allowing for internal as well as external quality control. BioMed Central 2014-12-04 /pmc/articles/PMC4267438/ /pubmed/25475407 http://dx.doi.org/10.1186/1477-7827-12-122 Text en © Kushnir et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Kushnir, Vitaly A Khanna, Pallavi Barad, David H Gleicher, Norbert Establishment of comparative performance criteria for IVF centers: correlation of live birth rates in autologous and donor oocyte IVF cycles |
title | Establishment of comparative performance criteria for IVF centers: correlation of live birth rates in autologous and donor oocyte IVF cycles |
title_full | Establishment of comparative performance criteria for IVF centers: correlation of live birth rates in autologous and donor oocyte IVF cycles |
title_fullStr | Establishment of comparative performance criteria for IVF centers: correlation of live birth rates in autologous and donor oocyte IVF cycles |
title_full_unstemmed | Establishment of comparative performance criteria for IVF centers: correlation of live birth rates in autologous and donor oocyte IVF cycles |
title_short | Establishment of comparative performance criteria for IVF centers: correlation of live birth rates in autologous and donor oocyte IVF cycles |
title_sort | establishment of comparative performance criteria for ivf centers: correlation of live birth rates in autologous and donor oocyte ivf cycles |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267438/ https://www.ncbi.nlm.nih.gov/pubmed/25475407 http://dx.doi.org/10.1186/1477-7827-12-122 |
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