Propensity Score Method for Partially Matched Omics Studies

This paper focuses on the problem of partially matched samples in the presence of confounders. We propose using propensity score matching to adjust for confounding factors for the subset of data with incomplete pairs, followed by integrating the P-values computed from the complete and incomplete pai...

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Detalles Bibliográficos
Autor principal: Kuan, Pei-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267441/
https://www.ncbi.nlm.nih.gov/pubmed/25535453
http://dx.doi.org/10.4137/CIN.S16352
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author Kuan, Pei-Fen
author_facet Kuan, Pei-Fen
author_sort Kuan, Pei-Fen
collection PubMed
description This paper focuses on the problem of partially matched samples in the presence of confounders. We propose using propensity score matching to adjust for confounding factors for the subset of data with incomplete pairs, followed by integrating the P-values computed from the complete and incomplete paired samples, respectively. Several simulations and a case study on DNA methylation are considered to evaluate the operating characteristics of the proposed method.
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spelling pubmed-42674412014-12-22 Propensity Score Method for Partially Matched Omics Studies Kuan, Pei-Fen Cancer Inform Review This paper focuses on the problem of partially matched samples in the presence of confounders. We propose using propensity score matching to adjust for confounding factors for the subset of data with incomplete pairs, followed by integrating the P-values computed from the complete and incomplete paired samples, respectively. Several simulations and a case study on DNA methylation are considered to evaluate the operating characteristics of the proposed method. Libertas Academica 2014-10-29 /pmc/articles/PMC4267441/ /pubmed/25535453 http://dx.doi.org/10.4137/CIN.S16352 Text en © 2014 the author(s), publisher and licensee Libertas Academica Ltd. This is an open-access article distributed under the terms of the Creative Commons CC-BY-NC 3.0 License.
spellingShingle Review
Kuan, Pei-Fen
Propensity Score Method for Partially Matched Omics Studies
title Propensity Score Method for Partially Matched Omics Studies
title_full Propensity Score Method for Partially Matched Omics Studies
title_fullStr Propensity Score Method for Partially Matched Omics Studies
title_full_unstemmed Propensity Score Method for Partially Matched Omics Studies
title_short Propensity Score Method for Partially Matched Omics Studies
title_sort propensity score method for partially matched omics studies
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267441/
https://www.ncbi.nlm.nih.gov/pubmed/25535453
http://dx.doi.org/10.4137/CIN.S16352
work_keys_str_mv AT kuanpeifen propensityscoremethodforpartiallymatchedomicsstudies

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