HIV-1 subtype influences susceptibility and response to monotherapy with the protease inhibitor lopinavir/ritonavir

OBJECTIVE: PI susceptibility results from a complex interplay between protease and Gag proteins, with Gag showing wide variation across HIV-1 subtypes. We explored the impact of pre-treatment susceptibility on the outcome of lopinavir/ritonavir monotherapy. METHODS: Treatment-naive individuals who e...

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Detalles Bibliográficos
Autores principales: Sutherland, K. A., Ghosn, J., Gregson, J., Mbisa, J. L., Chaix, M. L., Cohen Codar, I., Delfraissy, J. F., Delaugerre, C., Gupta, R. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267506/
https://www.ncbi.nlm.nih.gov/pubmed/25228587
http://dx.doi.org/10.1093/jac/dku365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267506/
https://www.ncbi.nlm.nih.gov/pubmed/25228587
http://dx.doi.org/10.1093/jac/dku365

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