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Safety and effective use of landiolol in the ICU
Supplemental landiolol administration (20 or 40 μg kg(-1) min(-1)) effectively diminished harmful hemodynamic changes during bronchoscopic endotracheal suctioning compared to normal saline. However, inappropriate use of landiolol (i.e., failure of evaluating factors that influence hemodynamic change...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267602/ https://www.ncbi.nlm.nih.gov/pubmed/25520832 http://dx.doi.org/10.1186/2052-0492-2-16 |
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author | Hifumi, Toru Kato, Hiroshi Koido, Yuichi Kawakita, Kenya Kuroda, Yasuhiro |
author_facet | Hifumi, Toru Kato, Hiroshi Koido, Yuichi Kawakita, Kenya Kuroda, Yasuhiro |
author_sort | Hifumi, Toru |
collection | PubMed |
description | Supplemental landiolol administration (20 or 40 μg kg(-1) min(-1)) effectively diminished harmful hemodynamic changes during bronchoscopic endotracheal suctioning compared to normal saline. However, inappropriate use of landiolol (i.e., failure of evaluating factors that influence hemodynamic changes) may iatrogenically further complicate pathophysiology, and relatively higher doses of landiolol may be dangerous. We recommend that landiolol should not be routinely used to control cardiovascular responses during bronchoscopic endotracheal suctioning in the intensive care unit. Careful evaluation of factors influencing hemodynamic changes and close monitoring of the patient are mandatory following landiolol administration. Furthermore, a lower initiation dose is recommended. |
format | Online Article Text |
id | pubmed-4267602 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-42676022014-12-17 Safety and effective use of landiolol in the ICU Hifumi, Toru Kato, Hiroshi Koido, Yuichi Kawakita, Kenya Kuroda, Yasuhiro J Intensive Care Letter to the Editor Supplemental landiolol administration (20 or 40 μg kg(-1) min(-1)) effectively diminished harmful hemodynamic changes during bronchoscopic endotracheal suctioning compared to normal saline. However, inappropriate use of landiolol (i.e., failure of evaluating factors that influence hemodynamic changes) may iatrogenically further complicate pathophysiology, and relatively higher doses of landiolol may be dangerous. We recommend that landiolol should not be routinely used to control cardiovascular responses during bronchoscopic endotracheal suctioning in the intensive care unit. Careful evaluation of factors influencing hemodynamic changes and close monitoring of the patient are mandatory following landiolol administration. Furthermore, a lower initiation dose is recommended. BioMed Central 2014-02-21 /pmc/articles/PMC4267602/ /pubmed/25520832 http://dx.doi.org/10.1186/2052-0492-2-16 Text en © Hifumi et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Letter to the Editor Hifumi, Toru Kato, Hiroshi Koido, Yuichi Kawakita, Kenya Kuroda, Yasuhiro Safety and effective use of landiolol in the ICU |
title | Safety and effective use of landiolol in the ICU |
title_full | Safety and effective use of landiolol in the ICU |
title_fullStr | Safety and effective use of landiolol in the ICU |
title_full_unstemmed | Safety and effective use of landiolol in the ICU |
title_short | Safety and effective use of landiolol in the ICU |
title_sort | safety and effective use of landiolol in the icu |
topic | Letter to the Editor |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267602/ https://www.ncbi.nlm.nih.gov/pubmed/25520832 http://dx.doi.org/10.1186/2052-0492-2-16 |
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