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HIV-1 transcription is regulated by splicing factor SRSF1
Efficient transcription of the HIV-1 genome is regulated by Tat, which recruits P-TEFb from the 7SK small nuclear ribonucleoprotein (snRNP) and other nucleoplasmic complexes to phosphorylate RNA polymerase II and other factors associated with the transcription complex. Although Tat activity is depen...
Autores principales: | Paz, Sean, Krainer, Adrian R., Caputi, Massimo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267630/ https://www.ncbi.nlm.nih.gov/pubmed/25416801 http://dx.doi.org/10.1093/nar/gku1170 |
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