The Mtr4 ratchet helix and arch domain both function to promote RNA unwinding

Mtr4 is a conserved Ski2-like RNA helicase and a subunit of the TRAMP complex that activates exosome-mediated 3′-5′ turnover in nuclear RNA surveillance and processing pathways. Prominent features of the Mtr4 structure include a four-domain ring-like helicase core and a large arch domain that spans...

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Detalles Bibliográficos
Autores principales: Taylor, Lacy L., Jackson, Ryan N., Rexhepaj, Megi, King, Alejandra Klauer, Lott, Lindsey K., van Hoof, Ambro, Johnson, Sean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267639/
https://www.ncbi.nlm.nih.gov/pubmed/25414331
http://dx.doi.org/10.1093/nar/gku1208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267639/
https://www.ncbi.nlm.nih.gov/pubmed/25414331
http://dx.doi.org/10.1093/nar/gku1208

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