Cargando…

DNA repair inhibition by UVA photoactivated fluoroquinolones and vemurafenib

Cutaneous photosensitization is a common side effect of drug treatment and can be associated with an increased skin cancer risk. The immunosuppressant azathioprine, the fluoroquinolone antibiotics and vemurafenib—a BRAF inhibitor used to treat metastatic melanoma—are all recognized clinical photosen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peacock, Matthew, Brem, Reto, Macpherson, Peter, Karran, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267641/ https://www.ncbi.nlm.nih.gov/pubmed/25414333 http://dx.doi.org/10.1093/nar/gku1213

Ejemplares similares

Identification of potentially cytotoxic lesions induced by UVA photoactivation of DNA 4-thiothymidine in human cells
por: Reelfs, Olivier, et al.
Publicado: (2011)

Reactive oxygen species generated by thiopurine/UVA cause irreparable transcription-blocking DNA lesions
por: Brem, Reto, et al.
Publicado: (2009)

Crosslinking of DNA repair and replication proteins to DNA in cells treated with 6-thioguanine and UVA
por: Gueranger, Quentin, et al.
Publicado: (2011)

Guanine sulphinate is a major stable product of photochemical oxidation of DNA 6-thioguanine by UVA irradiation
por: Ren, Xiaolin, et al.
Publicado: (2010)

UVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages
por: Greinert, R., et al.
Publicado: (2012)

UVA photoactivation of DNA containing halogenated thiopyrimidines induces cytotoxic DNA lesions
por: Brem, Reto, et al.
Publicado: (2015)

Oxidative stress induced by UVA photoactivation of the tryptophan UVB photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) inhibits nucleotide excision repair in human cells
por: Brem, Reto, et al.
Publicado: (2017)

Protein oxidation, UVA and human DNA repair
por: Karran, Peter, et al.
Publicado: (2016)

Inhibition of DNA damage repair by artificial activation of PARP with siDNA
por: Croset, Amelie, et al.
Publicado: (2013)

Disruption of PARP1 function inhibits base excision repair of a sub-set of DNA lesions
por: Reynolds, Pamela, et al.
Publicado: (2015)

Whole-exome sequencing reveals the impact of UVA light mutagenesis in xeroderma pigmentosum variant human cells
por: Moreno, Natália Cestari, et al.
Publicado: (2020)

The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis
por: Burkovics, Peter, et al.
Publicado: (2016)

Rad52 SUMOylation affects the efficiency of the DNA repair
por: Altmannova, Veronika, et al.
Publicado: (2010)

Homeostatic nuclear RAGE–ATM interaction is essential for efficient DNA repair
por: Kumar, Varun, et al.
Publicado: (2017)

Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin
por: Bacolla, Albino, et al.
Publicado: (2020)

An interplay of the base excision repair and mismatch repair pathways in active DNA demethylation
por: Grin, Inga, et al.
Publicado: (2016)

Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice
por: Jimeno, Sonia, et al.
Publicado: (2015)

Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair
por: Murray-Nerger, Laura A, et al.
Publicado: (2021)

Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair
por: Kalasova, Ilona, et al.
Publicado: (2020)

RAD51 interconnects between DNA replication, DNA repair and immunity
por: Bhattacharya, Souparno, et al.
Publicado: (2017)

The ATPase activity of Fml1 is essential for its roles in homologous recombination and DNA repair
por: Nandi, Saikat, et al.
Publicado: (2012)

The human DEK oncogene regulates DNA damage response signaling and repair
por: Kavanaugh, Gina M., et al.
Publicado: (2011)

Nucleotide excision repair of abasic DNA lesions
por: Kitsera, Nataliya, et al.
Publicado: (2019)

Dual daughter strand incision is processive and increases the efficiency of DNA mismatch repair
por: Hermans, Nicolaas, et al.
Publicado: (2016)

Timely termination of repair DNA synthesis by ATAD5 is important in oxidative DNA damage-induced single-strand break repair
por: Park, Su Hyung, et al.
Publicado: (2021)

Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
por: Zhao, Junhua, et al.
Publicado: (2009)

A functional screen identifies miRNAs that inhibit DNA repair and sensitize prostate cancer cells to ionizing radiation
por: Hatano, Koji, et al.
Publicado: (2015)

Evolutionary patterns of DNA base composition and correlation to polymorphisms in DNA repair systems
por: Li, Xianran, et al.
Publicado: (2015)

Stress-inducible NHEJ in bacteria: function in DNA repair and acquisition of heterologous DNA
por: Dupuy, Pierre, et al.
Publicado: (2019)

Catalytically inactive DNA ligase IV promotes DNA repair in living cells
por: Goff, Noah J, et al.
Publicado: (2022)

XRCC1 interacts with the p58 subunit of DNA Pol α-primase and may coordinate DNA repair and replication during S phase
por: Lévy, Nicolas, et al.
Publicado: (2009)

Role of polynucleotide kinase/phosphatase in mitochondrial DNA repair
por: Tahbaz, Nasser, et al.
Publicado: (2012)

Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage
por: Eccles, Laura J., et al.
Publicado: (2010)

Sumoylation of the Rad1 nuclease promotes DNA repair and regulates its DNA association
por: Sarangi, Prabha, et al.
Publicado: (2014)

LncRNA HOTAIRM1 functions in DNA double-strand break repair via its association with DNA repair and mRNA surveillance factors
por: Chuang, Tzu-Wei, et al.
Publicado: (2023)

NF-κB regulates DNA double-strand break repair in conjunction with BRCA1–CtIP complexes
por: Volcic, Meta, et al.
Publicado: (2012)

USP7/HAUSP stimulates repair of oxidative DNA lesions
por: Khoronenkova, Svetlana V., et al.
Publicado: (2011)

Dynamic binding of replication protein a is required for DNA repair
por: Chen, Ran, et al.
Publicado: (2016)

Proper RPA acetylation promotes accurate DNA replication and repair
por: Gan, Xiaoli, et al.
Publicado: (2023)

Lesion-specific DNA-binding and repair activities of human O(6)-alkylguanine DNA alkyltransferase
por: Melikishvili, Manana, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_m096a13gu7bdronskhu8bf61tt