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Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination

During meiosis programmed DNA double-strand breaks (DSBs) are repaired by homologous recombination using the sister chromatid or the homologous chromosome (homolog) as a template. This repair results in crossover (CO) and non-crossover (NCO) recombinants. Only CO formation between homologs provides...

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Detalles Bibliográficos
Autores principales: Lorenz, Alexander, Mehats, Alizée, Osman, Fekret, Whitby, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267644/
https://www.ncbi.nlm.nih.gov/pubmed/25414342
http://dx.doi.org/10.1093/nar/gku1219