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Abundance of the Fanconi anaemia core complex is regulated by the RuvBL1 and RuvBL2 AAA+ ATPases

Fanconi anaemia (FA) is a genome instability disease caused by defects in the FA DNA repair pathway that senses and repairs damage caused by DNA interstrand crosslinks. At least 8 of the 16 genes found mutated in FA encode proteins that assemble into the FA core complex, a multisubunit monoubiquitin...

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Detalles Bibliográficos
Autores principales:	Rajendra, Eeson, Garaycoechea, Juan I., Patel, Ketan J., Passmore, Lori A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267650/ https://www.ncbi.nlm.nih.gov/pubmed/25428364 http://dx.doi.org/10.1093/nar/gku1230

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