Constrained transcription factor spacing is prevalent and important for transcriptional control of mouse blood cells

Combinatorial transcription factor (TF) binding is essential for cell-type-specific gene regulation. However, much remains to be learned about the mechanisms of TF interactions, including to what extent constrained spacing and orientation of interacting TFs are critical for regulatory element activi...

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Detalles Bibliográficos
Autores principales: Ng, Felicia SL, Schütte, Judith, Ruau, David, Diamanti, Evangelia, Hannah, Rebecca, Kinston, Sarah J., Göttgens, Berthold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267662/
https://www.ncbi.nlm.nih.gov/pubmed/25428352
http://dx.doi.org/10.1093/nar/gku1254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267662/
https://www.ncbi.nlm.nih.gov/pubmed/25428352
http://dx.doi.org/10.1093/nar/gku1254

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