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Constrained transcription factor spacing is prevalent and important for transcriptional control of mouse blood cells
Combinatorial transcription factor (TF) binding is essential for cell-type-specific gene regulation. However, much remains to be learned about the mechanisms of TF interactions, including to what extent constrained spacing and orientation of interacting TFs are critical for regulatory element activi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267662/ https://www.ncbi.nlm.nih.gov/pubmed/25428352 http://dx.doi.org/10.1093/nar/gku1254 |