Cryo-electron tomography reveals ciliary defects underlying human RSPH1 primary ciliary dyskinesia

Cilia play essential roles in normal human development and health; cilia dysfunction results in diseases such as primary ciliary dyskinesia (PCD). Despite their importance, the native structure of human cilia is unknown, and structural defects in the cilia of patients are often undetectable or remai...

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Detalles Bibliográficos
Autores principales: Lin, Jianfeng, Yin, Weining, Smith, Maria C., Song, Kangkang, Leigh, Margaret W., Zariwala, Maimoona A., Knowles, Michael R., Ostrowski, Lawrence E., Nicastro, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267722/
https://www.ncbi.nlm.nih.gov/pubmed/25473808
http://dx.doi.org/10.1038/ncomms6727

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